Question?問題：

In recent years, tranexamic acid has been explored as a treatment for various causes of uncontrolled or coagulopathic bleeding in Emergency Medicine. What neurologic adverse effect has been reported after TXA administration??

近年來，氨甲環(huán)酸在急診醫(yī)學(xué)領(lǐng)域被用來治療多種難以控制或凝血障礙出血。已有報告顯示，在使用TXA后會出現(xiàn)什么神經(jīng)系統(tǒng)副作用？

Answer?答案：

TXA antagonizes the inhibitory neurotransmitter gamma-aminobutyric acid, which can increase seizure risk. High doses of TXA (> 100 mg/kg) are associated with an increased risk of seizure activity.?

TXA對抑制性神經(jīng)介質(zhì)胺基丁酸有抑制作用，增加癲癇危險。大劑量TXA（> 100 mg/kg）與增加癲癇風(fēng)險有關(guān)。

參考文獻(xiàn)：

Ann of EM, epub, 8/2/21