HIV-1 TAT (48-60) 是源自人免疫缺陷病毒 (HIV)-1蛋白殘基48-60，可滲透細(xì)胞的多肽。它已被用于以不中斷的方式將外源性大分子遞送到細(xì)胞中。

HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way.

編號(hào):179948

中文名稱:細(xì)胞穿膜肽TAT(48-60)

英文名:TAT(48-60)

單字母:H2N-GRKKRRQRRRPPQ-OH

三字母:H2N-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-COOH

氨基酸個(gè)數(shù):13

分子式:C70H131N35O16

平均分子量:1719.01

精確分子量:1718.05

等電點(diǎn)(PI):13.21

pH=7.0時(shí)的凈電荷數(shù):7.97

平均親水性:2.44

疏水性值:-3.49

來(lái)源:Synthetic

純度:95%、98%

鹽體系:可選TFA、HAc、HCl或其它

生成周期:2-3周

儲(chǔ)存條件:Powder -80°C 2 years -20°C 1 year In solvent -80°C 6 months -20°C 1 month

標(biāo)簽:<span class="nolink">細(xì)胞穿膜肽

參考文獻(xiàn)：

10.1016/s0006-291x(03)01135-5Uptake of analogs of penetratin, Tat(48-60) and oligoarginine in live cells

10.1002/cphc.200600306The cell-penetrating peptide TAT(48-60) induces a non-lamellar phase in DMPC membranes

10.1074/jbc.272.25.16010A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus